A MINDS Insight Retreat

Breakthrough thinking for a flourishing future

A 5-day research container in Mexico for AI engineers, innovators, founders, and alignment and safety researchers. Leave with a different way of seeing the world and your work within it.

Apply for the November 2026 cohort →

November 9–13, 2026  ·  Tandava Retreats, Mexico  ·  10–12 seats  ·  Application-based

In partnership with Tandava Retreats Scientific leadership from Manesh Girn, PhD and Simon Ruffell, MD, PhD Advised by Bruce Damer, PhD and Joseph Barsuglia, PhD

The Impasse

When more analysis stops producing new structure.

You know the feeling. You're engaged in a high-stakes problem. You know solving it can make a tremendous impact, and you want to make sure you do it exceptionally. You have all of the background knowledge and have thoroughly analyzed it, but the answer remains just out of reach. What you need is a different angle on the problem itself.

We built MINDS because the tools available for moving through this kind of impasse — design thinking, executive coaching, strategic offsites — operate where the impasse is not. They work with deliberate thought. The impasse sits upstream of that.

Why conventional methods fall short

Focused, linear thinking is what produced the impasse. More of that same kind of thinking rarely dissolves it.

What reorganizes a problem is a fundamental change in the cognitive frame that holds it — and, perhaps, in the person who is posing the question in the first place.

The Science

A growing body of research shows that altered states can powerfully reorganize how our brain represents and processes information.

This is the kind of insight we are interested in. The structural kind that emerges when a problem restructures itself, and, in a euphoric "Aha" moment, you are suddenly struck by a radically new solution that you can't believe you had been missing.

Psychedelic neuroscience has begun to characterize what Indigenous cultures have known for centuries, if not millennia.

Reduced rigidity of brain dynamics. Increased associative breadth in our semantic networks.

Looser priors, less stuckness in the familiar and known, and a temporary openness to new frameworks and perspectives that are received as visionary downloads.

These are the cognitive properties that frontier work demands and that conventional methods rarely access. This is what we mean when we describe MINDS as a think tank that operates at depth.

The 5-Day Arc

Evidence-based protocols that recalibrate how you see your work and the world at large. Drawing upon both cutting-edge science and Indigenous wisdom.

You arrive with a high-stakes problem critical to your work and close to your heart that you have been grappling with for some time.

Over five days, you move through a structured protocol developed by the Center for MINDS research team in collaboration with the facilitation team at Tandava. Five preparatory modules prime you by thoroughly characterizing your problem and bringing you to the outer edges of what you already know.

Two carefully held 5-MeO-DMT sessions do the transformative work to catalyze the breakthrough you need. Integration and follow-ups at one, four, and twelve weeks track what changes.

Tandava Retreats ceremony space, Mexico
Day 1

Arrive

Settling. Orientation. No cognitive work.

Day 2

Map

Problem representation, impasse construction, incubation.

Day 3

Primary Session

Higher-dose protocol day. Held container.

Day 4

Integrate

Lower-dose session, qualitative review, framework loosening.

Day 5

Depart

Outcome capture, integration plan, twelve-week roadmap.

Research participation is part of the program. See the FAQ for how your data is stored and protected.

Tandava Retreats estate, Tepotzlan Mexico
Tandava covered veranda and gardens
Tandava ceremony space, Tepotzlan
Tandava Retreat Center gardens
Tandava exterior, Tepotzlan Mexico

The Setting

Tandava — a decade of professional-grade psychedelic work.

Founded by Joel Brierre in the mountains just over an hour from Mexico City, Tandava has become the benchmark for professionally conducted 5-MeO-DMT retreats. The center operates purpose-built facilities designed around the specific demands of high-dose psychedelic work — private ceremonial spaces, experienced facilitation, medical infrastructure, and an environment calibrated to the depth MINDS requires. More than two thousand participants have moved through its protocols. The MINDS research container is built on that foundation.

Purpose-Built Environment

Private casitas, a spacious, expertly curated ceremony space, and dedicated integration spaces designed around the specific demands of 5-MeO-DMT work at therapeutic depth.

Expert Facilitation

Joel Brierre and his team have facilitated thousands of 5-MeO-DMT sessions over more than a decade, refining protocols across diverse populations and settings.

Medical Infrastructure

Full pre-screening, on-site clinical monitoring, and post-session support. Safety and hospitality are paramount and a core part of the center's ethos.

Curated Nutrition

Delicious, home prepared meals with our talented chefs throughout the retreat.

Participant Accounts

The container that Victoria and Joël and the entire crew at Tandava created was the sweetest safest warmest nest to allow me to go deep into my own process and still maintain connection with everyone. This retreat far surpassed any expectations I had.

Therapist

My experience has been life changing — and I firmly believe that is because of the combination of 5-MeO-DMT AND the container established and set by Joel and Victoria at Tandava Retreats. The medicine alone is not the answer. The container is.

Combat Veteran

Their mastery is undeniable, and I firmly believe that their skill and expertise in creating a secure and thoughtful container significantly shaped my experience.

Business Owner

They do not force anything onto you. When I could only take the medicine the first day, they supported me with meditation — I felt completely held throughout.

Retreat Participant

I am deeply appreciative for the individualized care I received from my facilitators. The attention to each person's process set this experience apart from anything I had imagined.

Retreat Participant

The Team

Scientists holding the protocol. Veteran facilitators holding the medicine.

The MINDS team brings together cognitive neuroscience, clinical psychiatry, and operational rigor. The facilitation team at Tandava brings two decades of work with 5-MeO-DMT in ceremonial and therapeutic settings.

Joel Brierre

Joel Brierre

Founder & Lead Facilitator
Tandava Retreats

Manesh Girn

Manesh Girn, PhD

Leading Psychedelic Neuroscientist & Biotech Founder
Previous Postdoctoral Scholar, UCSF
Scientific Director, Center for MINDS

Simon Ruffell

Simon Ruffell, MD, PhD

Senior Research Fellow, University of Exeter
Chief Medical Officer, Center for MINDS

Joshua Barber

Joshua Barber

Founder, Axis Mundi Partners
Co-Founder, Enthea
Interim CEO, Center for MINDS

Advised by

Bruce Damer, PhD  ·  Astrobiologist, Co-founder MINDS
Joseph Barsuglia, PhD  ·  Psychedelic Researcher

Facilitation Partner

Tandava Retreats, Mexico
Two decades of work with 5-MeO-DMT.

The Outcome

Come with a problem that matters. Leave with the capacity to see it differently.

The work continues after the retreat. Here is what you take with you.

The cohort is small (10–12) and selected with care. The relationships formed here tend to outlast the retreat by years.

Eligibility

This retreat is built for changemakers carrying a problem that genuinely matters.

Built for

  • AI engineers, innovators, founders, and alignment or safety researchers
  • Prior psychedelic experience or substantial readiness
  • Able to engage seriously with research data collection
  • Carrying a concrete, professionally embedded problem

Not the right container for

  • First-time psychedelic experiences
  • Trauma processing or therapeutic-primary goals
  • A vacation, vision quest, or retreat in the conventional sense
  • Abstract or aspirational problems without professional stakes

Ten to twelve seats. A small number are reserved under our Eleusinian Fellowship for high-leverage researchers sponsored by aligned philanthropic partners.

For the Still-Curious

Questions worth asking.

Is there a fee?
No. The inaugural cohort is fully funded by a philanthropic research grant — there is no program fee, and lodging, meals, facilitation, and the full research protocol are covered. A refundable $500 deposit holds your seat and is returned to you on arrival. Travel to Mexico is not included.
What is the screening process?
After your application, we schedule a 30-minute call to ensure mutual fit. Selected applicants then complete a medical screening with our clinical team. Final acceptance is contingent on both fits being clear.
Do I have to participate in the research?
These are funded research seats, so participation in data collection is part of the program. What remains optional is whether you appear in any photography, video, or written testimonial — that’s a separate, opt-in choice with several levels, and you can withdraw it at any time.
Is my participation confidential?
Research data is stored under a participant code. Your identifying details are held separately from your research data, the key is kept offline and restricted to a single member of the research team, and it is destroyed after the twelve-week follow-up. Interview recordings are deleted once transcribed. We do not collect your employer.
What happens if I am not selected?
We try to give specific, useful feedback. Many applicants who are not the right fit for the inaugural cohort are strong candidates for later programs. We will tell you which applies.
Can I bring a partner or co-founder?
Each application is individual. Cohort composition is curated to support both the research and the group dynamic. Co-founder pairs and team applications are evaluated separately under our Founder Team Protocols.
What is the refund policy?
The $500 deposit is returned to you in full on arrival. It is forfeited in the case of a no-show, and it is transferable to a future cohort if you let us know in advance.

2027 Retreats

Can’t make it this time? Join the waitlist for 2027 retreats.

Leave your details and we’ll be in touch when dates for future retreats are set.

November 2026

Ten to twelve seats.
One inaugural cohort.

Applications close October 26, 2026 at 11:59pm PT, or when the cohort is full.

Start your application →

Takes about 15 minutes. We respond within 5 business days.

2027 Retreats

Join the waitlist

Can’t make November? Leave your details and we’ll be in touch when dates for future retreats are set.

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